李敬源教授
学习经历
1998-2007 皇冠物理系,本科,
2002-2007 皇冠物理系,研究生
工作经历
2007-2011 美国哥伦比亚大学化学系,博士后
2011-2017 中国科学院高能物理研究所,研究员
2017-至今 皇冠物理系,教授
研究领域
软凝聚态物理,生物物理
利用分子动力学等模拟方法并发展有针对性的计算分析方法,研究蛋白质等生物分子与外界环境的相互作用及其界面行为,对一些生命过程以及纳米材料的生物学效应进行讨论。
代表出版物
1. Zhonghe Xu, Shuang Zhang, Jeffrey K. Weber, Binquan Luan, Ruhong Zhou, and Jingyuan Li*, “Sequential protein unfolding through a carbon nanotube pore”, Nanoscale (2016) 8, 12143‑12151 (Cover Article)
2. Deyi An, Jiguo Su, Jeffrey K. Weber, Xueyun Gao, Ruhong Zhou*, Jingyuan Li*, “A Peptide‑Coated Gold Nanocluster Exhibits Unique Behavior in Protein Activity Inhibition”, J. Am. Chem. Soc. (2015) 137, 8412‑8418
3. Liming Wang†, Jingyuan Li†, Jun Pan, Xiumei Jiang, Yinglu Ji, Yufeng Li, Ying Qu, Yuliang Zhao, Xiaochun Wu*, Chunying Chen*, “Revealing the Binding Structure of the Protein Corona on Gold Nanorods Using Synchrotron Radiation‑Based Techniques: Understanding the Reduced Damage in Cell Membranes”, J. Am. Chem. Soc. (2013) 135, 17359‑17368
4. Jingyuan Li, Julio M. Fernandez, and Bruce Berne, “Water’s Role in the ForceInduced Unfolding of Ubiquitin”, Proc. Natl. Acad. Sci. USA(2010) 107, 19284‑19289
5. Lorna Dougan, Jingyuan Li, Carmen L. Badilla, Bruce J. Berne, and Julio M. Fernandez, “Single homopolypeptide chains collapse into mechanically rigid conformations”, Proc. Natl. Acad. Sci. USA. (2009) 106, 12605‑12610
6. Jingyuan Li, Xiaojing Gong, Hangjun Lu, Ding Li, Haiping Fang, and Ruhong Zhou, “Electrostatic gating of a nanometer water channel”, Proc. Natl. Acad. Sci. USA, (2007) 104, 3687‑3692
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